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TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

MMBD can be formed by head-to-tail dimerization of two o -toluidine units, and its formation was shown to be dependent on active S9 in the presence of NADPH as a cofactor

doi: 10.3389/fpls.2022.879642 40 LiR.FuD.ZhuB.LuoY.ZhuH

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The mice were then decapitated and the entire brain was removed and immediately submerged in ice-cold, carbogen-saturated (95% O 2 and 5% CO 2 ) aCSF (126 mM NaCl, 2.8 mM KCl, 1.2 mM MgCl 2 , 2.5 mM CaCl 2 , 1.25 mM NaH 2 PO 4 , 26 mM NaHCO 3 and 5 mM glucose)