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Golvatinib also greatly reduced tumor burden in mouse xenograft models and blood vessel density in remaining tumors

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The Institute of Medicine recommends a daily dietary copper intake of 0.9 mg for adults, with a tolerable upper limit of 10 mg/day to prevent liver toxicity (Trumbo et al., 2001)

The polymer moiety can be soluble or insoluble, existing for example as dispersed micelles or particles, such as colloidal particles or (insoluble) macroscopic beads