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Stress can reduce growth performance, damage liver structure, and disrupt hepatic glucose metabolism and lipid metabolism 6

Effect of the insulin sensitizer pioglitazone on insulin resistance, hyperandrogenism, and ovulatory dysfunction in women with polycystic ovary syndrome

however, there were statistically significant improvements in MMS between baseline and week 24 in cohort 2 (change = 0.33 dB, 95% CI: 0.020.64, P = 0.04) and cohort 3 (change = 0.85 dB, 95% CI: 0.291.42, P = 0.003

Bartoszewski, J

Therefore, alterations in these microbial metabolites suggest the involvement of gut microbes in the development of depression, while further studies investigating the underlying pathogenic bacterium are still warranted