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Several potential mechanisms underlying the pathogenesis of PD have been proposed: (1) Oxidative Stress (OS): Under normal circumstances, a steady-state balance exists between oxidative and antioxidant systems within the body

Jacobs, S

Through PLGA degradation, lactate is released that can potentially provoke the proliferation of endothelial and fibroblast cells (Porporato et al., 2012)

Coronary Disease: It helps with shortness of breath and improves symptoms

Despite some cases of acute toxicities or symptomatic radionecrosis, combined HBOT with radiochemotherapy is noted to be safe and tolerable for patients (156, 163, 164)