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For example, curcumin in nanoformulation and liposomal encapsulated has been investigated to circumvent poor systemic absorption and enhance targeting into tumour tissue to permit accurate discovery of dose-response relationship as well as pharmacodynamic effects in vivo (229)

Greenburg G, Hay ED (1986) Cytodifferentiation and tissue phenotype change during transformation of embryonic lens epithelium to mesenchyme-like cells in vitro