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Fontana F, Molinaro G, Moroni S, Pallozzi G, Ferreira MPA, Tello RP, Elbadri K, Torrieri G, Correia A, Kemell M, et al

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- Lapachone (ARQ761) induces DNA damage, PARP1 hyperactivation, and apoptosis in an NQO1-dependent manner (NCT02514031)

The transition from the lab to testing in humans is one of the most important steps in drug development