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10.1016/j.ccell.2018.01.001 173

Initial Treatment in Combination with Pembrolizumab and Platinum The efficacy of pemetrexed in combination with pembrolizumab and platinum chemotherapy was investigated in Study KEYNOTE-189 (NCT02578680), a randomized, multicenter, double-blind, active-controlled trial conducted in patients with metastatic non-squamous NSCLC, regardless of PD-L1 tumor expression status, who had not previously received systemic therapy for metastatic disease and in whom there were no EGFR or ALK genomic tumor aberrations

Stimulates Blood Vessel Formation BPC-157 promotes angiogenesis, the formation of new blood vessels

This can exhibit as weariness, a lack of motivation, tiredness, and feeling weak

What are the reported side effects of peptides in BPC-157 studies