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These remaining coca alkaloids have been used by indigenous Andean peoples for thousands of years in the leaf form for energy, altitude adaptation, hunger suppression, and fatigue resistance

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A separate 2025 network meta-analysis compared multiple supplements head-to-head for men with unexplained infertility and found that both L-carnitine and CoQ10 improved semen quality versus placebo

However, those who took Cognizin showed modest improvements in visual memory and new learning and composite memory (Nakazaki, J Nutr 2021)

Graphical Abstract Similar content being viewed by others Introduction Chemotherapy-induced cognitive impairment (CICI), termed chemobrain or chemofog, refers to the state of extended cognitive impairment resulting from the administration of a variety of chemotherapeutic agents including doxorubicin, cyclophosphamide, 5-fluorouracil, and methotrexate (Christie et al