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The allosteric activator TEPP-46 inhibits the expression of glycolytic genes by inducing pyruvate kinase M2 (PKM2) tetramerization and blocking its nuclear translocation

doi: 10.1155/2014/289264 168 CaoRYZhangYFengZLiuSLiuYZhengHet al

[40] Currently there is some concern regarding supplementation with carotenoids, [41] as beta-carotene has been associated with higher risk of lung cancer in smokers, but not in the general population

Lower concentrations mean larger volumes but easier accurate measurement

These findings suggest that the aspirin-induced increase in intracellular glutamine levels is regulated at both the levels of de novo synthesis and import from the extracellular environment