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Anakinra is a recombinant human interleukin 1 receptor antagonist used to treat rheumatoid arthritis, systemic juvenile idiopathic arthritis, adult-onset Still disease, and, in select patients, recurrent pericarditis

Given that the cellular concentration of tubulin is generally estimated to be approximately 25 M in non-neuronal cells 38 and even higher in neurons 39 , the EpoB-to-tubulin ratio in our experiments was significantly (three orders of magnitude) lower than those used in prior in vitro experiments to visualize epothilonetubulin complexes (0.2 to 0.5 mM epothilone) 22,23,24

J Clin Med 14(3)

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The result is an exosome product that can be used to send consistent, pro-repair signals to targeted tissues