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Regulatory T cells in the TME depend on OXPHOS [228, 229]

& El-Demerdash, S

Ascorbate attenuates the systemic kainate-induced neurotoxicity in the rat hippocampus

Despite the pronounced metabolic changes (221), there is a paucity of experimental and clinical research on pregnant and lactating women in drug metabolism (222224), hence their designation as therapeutic orphans (37)