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Description

The heart-rate cost is mostly the glucagon arm: GLP-1 on its own nudges heart rate up a little and then flattens, while glucagon carries the part that keeps climbing with the dose

This multi-receptor approach distinguishes it from existing licensed medicines such as semaglutide (Ozempic, Wegovy) or tirzepatide licensed in the UK as Mounjaro for type 2 diabetes and as Zepbound for obesity which act on fewer receptor pathways

This is because your body will absorb only as much as it needs, and the rest will pass through your pee

When someone is genuinely deficient, or even borderline low, the difference can be quite remarkable

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