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Funding This work was supported by the Centre National de la Recherche Scientifique, the Agence Nationale de la Recherche (ANR-Blanc Cynthiol 12-BSV6-0011)

We note that Mallinckrodt Hospital Products, Inc

Therefore, we regard our ITC data as relative measurements of both SAM binding and conformational changes

Therefore, melatonin is believed to reduce the status of CIPN by limiting the development of mechanical hypersensitivity and altering peripheral nerve function