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All cells were maintained in an incubator at 37 C with 5% CO2 and 95% air

Notably, treatment with marmelosin at doses of 10 and 20 mg/kg resulted in a marked increase in body weight

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Quercetin has been observed to stimulate autophagy in various models and conditions, including diabetic nephropathy (Wang et al., 2020), and retinal pigment epithelial cells under oxidative stress ( In studies, quercetin administration showed dose-dependent effects on autophagy induction

Yes, AOD-9604 is most effective when administered in a fasted state