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J Assist Reprod Genet (2002) 19(1):2430

Piera JM

NOX4 can generate and accumulate superoxide and hydrogen peroxide, thereby promoting lipid peroxidation and the onset of ferroptosis

In the pathogenesis of atherosclerotic plaque in the arterial wall, an accumulation of macrophages with inflammatory properties has been identified ( Obesity, type 2 diabetes and insulin resistance, hypertension and atherosclerosis contribute to the development and progression of both CVD and CKD ( Types of macrophages Macrophages are cells of the innate immune system and belong to the large family of mononuclear phagocytes