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Description

Trifylli, E

Animal experiments use intraperitoneal (i.p.), intravenous (i.v.), and intrathecal (i.t.) administration methods

HSP90 inhibitors have shown promise in preclinical models of autoimmune diseases such as arthritis and SLE by suppressing inflammatory signaling pathways

The affinity of such GC-mediated antibody responses increases with time after a single antigen exposure but also progressively with each new cognate antigen contact