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pDNA concentration and purity were measured on a NanoDrop One (Thermo Fisher, UK), and then linearized using MluI for 3 h at 37 C, followed by heat inactivation at 80 C for 20 min

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However, whereas the pharmacotherapy literature in cirrhosis has focused primarily on safety, the challenge with non-pharmacologic modalities is the near-absence of efficacy data specific to this population