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Phosphodiesterase 5 (PDE5) inhibitors have powerful protective effects against diabetic cardiomyopathy, and this may be dependent on H 2 S generation ( via promoting cardiac H 2 S biosynthesis and subsequent prevention of cardiomyocyte pyroptosis (Kar et al., 2019b)

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HPV vaccines have been developed to prevent HPV-associated cancer, external genital lesions, and genital warts ( R ) were administered twice a week at bedtime for 24 weeks, without any other medication for the whole study period