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They are stable for up to five hours in aqueous solution

mRNA-based therapeutics-developing a new class of drugs

The primary theory is that SF elicits oxidative stress and cellular damage (Shamsuzzaman et al., 2003)

PHD activates the pseudohypoxic response by stabilizing HIF-1, which is a well-known tumorigenesis enhancer, and as a transcription factor, maintains the metabolic reprogramming of cancer cells to support their survival 127

NOX1 is expressed in epithelial cells in the colon, placenta, prostate, and uterus, as well as in vascular smooth muscle cells, astrocytes, microglia, neural cells, and retinal pericytes