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Finally, cGMP activates the protein kinase C (PKC), leading to exocytosis of gonadotropine (Karanth et al., Vitamin C, learning, and memory Parle and Dhingra injected doses of 60 and 120 mg/kg of ascorbic acid intraperitoneally to mice with drug-induced amnesia via the administration of diazepam and scopolamine and to mice that acquired amnesia naturally with age (Parle and Dhingra, Studies conducted in our laboratory have demonstrated that vitamin C effects on learning and memory are dependent on the redox balance state

Nevertheless, if a patient develops significant neuropathy during treatment, consideration of stopping the offending drug(s) or reducing the dose is appropriate

Dysfunctional mitochondria generate excessive reactive oxygen species (ROS), perpetuating a vicious cycle that further aggravates neurotoxicity (Yan et al., 2021

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