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In this biosynthesis process, methionine is a critical source of cysteine to synthesize glutathione through methionine adenosyltransferase, S-adenosylhomocysteine hydrolase, cystathionine -synthase, cystathionine -lyase, GS, and so on [32]

They are needed for the maintenance of muscle during physical stress and exercise

Atherosclerosis.

It plays a role in metabolism of amino acids and is a necessary co-factor in the folate cycle, lack of which can lead to anemia

Although proximal steps (upstream events) in the development of DILI are likely to be drugs/class specific, distal steps (downstream events) are likely to be shared by DILI due to multiple drugs, so may have common biomarkers