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Nervousness or Anxiety: Some users report feelings of restlessness, anxiety, or jitteriness

G., Hopcroft, M

97, 349359, Epub 2012 Oct 31 10.1093/cvr/cvs330 [DOI] [PubMed] [Google Scholar] 68.Gao X., Li J

Because it is water-soluble, excess is typically excreted through the kidneys rather than accumulating to toxic levels, making supplementation generally safe even at high therapeutic doses