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doi: 10.1126/science.1126863 168 KampWMWangPYHwangPM

Li X, Liu C, Mao Z, Xiao M, Wang L, Qi S, et al

Conclusion Is It Worth the Risk

The ability to regulate sensory input by filtering out irrelevant stimuli (to prevent sensory overflow) can also be enhanced by opioid agonists, as suggested by a study where a low dose of morphine (10 mg PO) in 18 males enhanced modulation of the startle reflex to a noise burst following a prestimulus, a phenomenon called prepulse inhibition (Quednow et al., 2008)