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5 Integrated mechanisms linking periodontitis, microbiota, and depression Gut dysbiosis is recognized as a significant risk factor for depression, potentially influencing brain function and behavioral expression by altering immune system activation, neurotransmitter synthesis, and the production of metabolic byproducts

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Intra-assay CV values were calculated from data collected in triplicate and are found in the supplementary materials (S1 Table)

This process was repeated until the sample was entirely eluted to colorless