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In the absence of this enzyme, instability may occur in the midpiece of the spermatozoa, and defects in sperm motility may occur due to this instability

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Unusual lipid metabolism in various cells, such as cholesterol accumulation in macrophages within atherosclerotic plaques, can also stimulate NETosis, due to excessive secretion of IL-1 by these macrophages (151) ( Figure 3 )