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SNP identification and genotyping We extracted genomic DNA from peripheral leukocytes using the Qiagen Blood DNA Mini Kit (Qiagen Inc., Valencia, CA, USA) following the standard protocols

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The binding constant of HSA to A 42 was measured to be significantly higher than that of A 40 , an affinity gradient that corresponds to the greater pathogenicity of A 42 , suggesting that HSA has a selective advantage in targeting the more neurotoxic A isoforms [71]

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The lateral line of fish consists of mechanosensory organs called neuromasts, and the number, size and sensitivity of neuromasts to sensory stimuli are more profound in cavefish than in surface-dwelling populations (Yoshizawa et al