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Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood

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These are active areas of research, in particular given the continued emergence of new lineages of new variants

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found that EGCG has prophylactic effects on lupus nephritis in these mice that are highly associated with its effects of enhancing the Nrf2 antioxidant signaling pathway, decreasing renal NLRP3 inflammasome activation, and increasing systemic Treg cell activity [22, 25]