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Moreover, the affinity of Acs1 for acetate is reported to be several times greater than that of the constitutively expressed Acs2 isoform, suggesting that Acs1 is primarily responsible for acetyl-CoA synthesis during growth on non-fermentable carbon sources such as ethanol 26

Oral delivery of the vancomycin derivative FU002 by a surface-modified liposomal nanocarrier

The results imply that even residues not directly involved in the interaction may exhibit changes in their chemical environment if they are adjacent to residues crucial for the interaction or undergo conformational changes upon binding 39,40

doi: 10.18097/PBMC20226803228

Renal cortical and medullary tissues were collected and stored in the RNA later solution (Thermo Fisher Scientific Inc.) until use