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The critical question lies in determining whether elevated circulating metabolite concentrations represent disease-driving factors or secondary manifestations of excretory dysfunction

Betsy A, Binitha M, Sarita S

H 2 S was found to inhibit pulmonary arterial endothelial cell inflammation and prevent vascular remodeling, likely by suppressing the NF-B signaling pathway and endothelial-mesenchymal transition (EndMT) (Zhang D