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Regulation, function, and dysregulation of endocannabinoids in models of adipose and -pancreatic cells and in obesity and hyperglycemia

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In a multivariate logistic regression model, it was found that the presence or absence of MS was the only independent predictor of endothelial dysfunction (55).The occurrence of endothelial dysfunction represents an initial pathogenic occurrence in the development of MetS

Therefore, future research directions should include an in-depth study of ferroptosis, identification of key targets in the ferroptotic pathway and validation of their relationships in glioma and neuroblastoma, application of ferroptosis biomarkers in clinical prevention and monitoring, exploration of a new generation of ferroptosis-targeting systems, and finally, validation of the relationship between immunity and ferroptosis in glioma and neuroblastoma

doi: 10.1186/s12943-022-01657-y 184 DuFYangL-HLiuJWangJFanLDuangmanoSet al