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Catalytic mechanism of NADP(+)-dependent isocitrate dehydrogenase: implications from the structures of magnesium-isocitrate and NADP+ complexes

Lennon, D

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Diabetic patients: the administration of L-carnitine in diabetic patients treated with insulin or with oral hypoglycemic agents, improving the utilization of glucose, could lead to hypoglycemia phenomena

In such a way that unoxidized fatty acids are rerouted toward the synthesis of diacylglycerol and ceramide, which in turn stimulate stress-induced protein kinases that inhibit insulin signaling (89, 90)