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Although no difference in Gpx4 protein levels was observed in asymptomatic SOD1 G93A mice (data shown in Supplementary Material), symptomatic SOD1 G93A mice showed a significant decrease of Gpx4 protein (~ 43% reduction) compared with age-matched WT mice (Fig

This makes them ideal for studying early disease pathogenesis and for testing novel therapeutics like gene therapy or inhaled drugs

Your body releases it from extracellular matrix proteins whenever tissue damage occurs, essentially functioning as a biological signal that activates repair mechanisms

Eur J Biochem 2004;271:1814-9.ArticlePubMed 73

Biomaterials 26 , 54745491 (2005)