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Keratin 17 (K17) is pivotal in psoriasis pathogenesis: its abnormal overexpression drives excessive keratinocyte (KC) proliferation, inhibits apoptosis, and functions as an autoantigen to activate T cells, particularly Th17 cells, to induce the secretion of cytokines such as IL-17 and IL-23

Carboxytherapy is considered a safe, minimally invasive treatment when performed by trained medical professionals

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It uses low-molecular collagen

Managing gastrointestinal side effects, particularly nausea, requires a multifaceted approach that may include both behavioral modifications and potential medical interventions