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For quantitation, calibration curves were constructed from at least six consecutive calibrators in the range from 1 to 4000 ng/ml, covering the relevant concentration ranges in the samples

Leucinerich repeat kinase 2 (LRRK2) mutations were first identified in 2004 to cause autosomal dominant PD [196, 197]

Gotzl JK, Colombo AV, Fellerer K, Reifschneider A, Werner G, Tahirovic S, Haass C, Capell A

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Interestingly, the findings showed that spermidine improves skin health indirectly by reshaping the skin microbiome and restoring microbial functions that protect the epidermis