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When the calcium concentration reaches a critical level, insulin is secreted through the process of exocytosis by large, dense core vesicles

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Primary MS fatigue is intricately linked to the disease process

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Lloyd MM, Grima MA, Rayner BS, Hadfield KA, Davies MJ, Hawkins CL (2013) Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells