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Duffin R, Gilmour PS, Schins RP, Clouter A, Guy K, Brown DM, MacNee W, Borm PJ, Donaldson K, Stone V

MELD-3 improvement in HCC patientsincluding within Cluster two where HCC prevalence was 34.9% likely reflects tumour-directed therapies or fluctuations in hepatic reserve unrelated to antioxidant supplementation, and should not be interpreted as evidence of glutathione efficacy

Reduced production of peroxided lipids and induction of iron overload were observed in an ACSL4 conditional deletion mouse, conversely, the phenotype was reversed upon overexpression of ACSL4

On the other hand, 8-prenylnaringenin has also been found to inhibit aromatase, an enzyme involved in estrogen synthesis, in the laboratoryan effect that could potentially lower E2 levels

First-in-humans evaluation of 18 F-SMBT-1, a novel 18 F-labeled monoamine oxidase-B PET tracer for imaging reactive astrogliosis