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The B12-IF complex is absorbed by cells in the final section of the small intestine (the ileum), where IF is cleaved from B12 and subsequently, B12 passes into the blood where transport proteins bind to it and is distributed to cells all around the body (Obeid et al., 2015

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But clinical data, dosing, and understanding of the broader effects in humans lacks study

The paper is Awosemo et al

Together, the combination makes it easier to stick to mindful eating habits with far less internal resistance