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Clin Exp Ophthalmol 1990

Stafforini DM, Sheller JR, Blackwell TS, Sapirstein A, Yull FE, McIntyre TM, Bonventre JV, Prescott SM, Roberts LJ 2nd

Less commonly used supplements included vitamin B 12 or vitamin B complex (72 patients), fish oil (51 patients), magnesium (29 patients), coenzyme Q10 (15 patients), cannabis products (12 patients), turmeric or curcumin (11 patients), calcium (9 patients), folic acid (9 patients), zinc (9 patients), probiotics (7 patients), iron (6 patients), vitamin C (5 patients), various organ-support products (3 patients), alpha-lipoic acid (2 patients), biotin (2 patients), Boswellia complex (2 patients), melatonin (2 patients), and 1 report each of acetyl-L-carnitine, ashwagandha, black cohosh, cranberry extract, ginger oil, ginseng, green tea extract, lysine, nettle leaf, oregano oil, primrose oil, and valerian root

Further, these investigational agents are targeting a range of pathological mechanisms including protein homeostasis and neuroinflammation

H.et al (2013)