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These data not only provide new mechanistic insight into the role of EHBP1 in hepatic cholesterol metabolism and NASH fibrosis by uncovering the interaction between EHBP1 and other LDL cholesterol-related loci including SORT1, PCKS9, and LDLR, but also elucidate a novel interplay between inflammation and EHBP1-mediated cholesterol metabolism in the context of NASH

10.1038/s41586-019-1707-0 40 DollS.PronethB.TyurinaY

Beyond detoxification, it may support a healthy immune response and promote the maintenance of cellular energy levels

Crystal structure of human estrogen-related receptor alpha in complex with a synthetic inverse agonist reveals its novel molecular mechanism

Manufacturer: Elabscience Succinic acid, also known as succinic acid, is widely present in all plant and animal tissues, was first extracted from amber, is an intermediate in the citric acid cycle, and plays an important role in the production of energy in cells