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10.1016/j.biopsych.2014.11.010 202 MiaoL.YangY.LiuY.LaiL.WangL.ZhanY.et al

In a 10-year follow up to the AREDS2, participants who had been randomized to receive lutein plus zeaxanthin had a 20% lower risk of progressing to late AMD than those who had been given beta-carotene (Chew 2022)

Primary keratinocytes were obtained from foreskin circumcisions of fair-skinned donors (03 years of age, parental written informed consent), established in cell culture and cultured for maximal 3 weeks as previously described 44