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NFkB increases the transcription of HIF1 in response to many pathological conditions such as hypoxia and bacterial invasion [81]

Giornale Ital Ricerche Clin Ter

Bone-specific nutrients: Calcium (1000-1200mg daily from diet and supplements), vitamin D (2000-4000 IU daily achieving blood levels 40-60 ng/mL), vitamin K2 (directing calcium to bones versus soft tissues), magnesium (cofactor in bone metabolism)