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rising evidence supports that MGB axis establishes a bidirectional connection, so that central injury not only disrupts CNS, but also causes a gastrointestinal injury [108]

and Heller, W.P

Growth hormone-releasing factor from a human pancreatic islet tumor

Extracellular L-lactate released by astrocytes, either generated from recently captured glucose or from glycogen, binds to HCAR1, a specific perivascular and post-synaptic receptor, regulating synaptic plasticity