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The C419A (NCBI SNP cluster ID, rs 4925) polymorphism in GSTO-1 gene has been reported to be involved in stroke [22]

Oral glutathione at recommended doses (up to 500mg/day) has a strong safety profile in published literature

Alcoholism: Clinical and Experimental Research 34 , 251261, doi: 10.1111/j.1530-0277.2009.01088.x (2010)

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Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations GSH: reduced glutathione GSSG: glutathione disulfide GS: thyil radical ROS: reactive oxygen species RNS: reactive nitrogen species RS: reactive species -GCS: -glutamylcysteine synthetase GPX: glutathione peroxidase GR: glutathione reductase GST: glutathione S -transferase GSNO: nitrosoglutathione G6PD: glucose-6-phosphate dehydrogenase NAC: N -acetyl-L-cysteine NO: nitric oxide protein-SSG: protein glutathionylation protein-SNO: protein nitrosylation References Galluzzi L, Maiuri MC, Vitale I, Zischka H, Castedo M, Zitvogel L et al