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Given its potent redox capabilities, and its high intracellular concentration and widespread distribution, its role as a potent defense mechanism against oxidative and electrophilic stress is well-established

A key 6-year follow-up study (N=266, elderly patients aged 60-89) published in Bulletin of Experimental Biology and Medicine demonstrated that Epithalamin treatment normalized melatonin production, improved T-cell immunity markers (CD3+, CD4+, CD4/CD8 ratio), and reduced cardiovascular mortality by 28% compared to the control group