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Description

Growth Hormone differentially modulates chemoresistance in human endometrial adenocarcinoma cell lines

230 This modification can improve the resistance of nucleic acids to nucleases, enhance blood stability, reduce renal clearance, and prolong the circulation time of drugs in vivo by improving their binding to plasma proteins

FDA described the clinical evidence as inconclusive and preliminary and identified product-characterisation, aggregation, immunogenicity and safety uncertainties