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Tateishi et al, 2017), and the development of NAD + biosynthetic inhibitors targeting nicotinamide phosphoribosyltransferase (NAMPT) to treat cancer (Tateishi et al, 2017

doi: 10.1136/esmoopen-2016-000138 220 ShenR.ChenS.LeiW.ShenJ.LvL.WeiT

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Isoform-specific binding of selenoprotein P to the -propeller domain of apolipoprotein E receptor 2 mediates selenium supply

Furthermore, stratified management optimizes resource allocation by prioritizing patients with the highest predicted benefit, improving therapeutic success rates while enhancing safety through personalized risk mitigation (177)