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Although PCC diagnosis was based on the WHO criteria available in 2020 29 , it is now recognized that PCC incidence and predominant symptom profiles can vary depending on the SARS-CoV-2 variant in circulation at the time of infection 70

Of relevance, earlier studies have shown that human islets are more resistant to oxidant-generating beta cell toxins such as alloxan, streptozotocin, nitroprusside or cytokine-induced injury than mouse islets (Welsh et al