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It plays a crucial role in liver homeostasis and lipid metabolism

GSH, in turn, plays a pivotal role in detoxifying lipid peroxides via GPX4, thereby preventing ferroptosis, a form of regulated cell death characterized by excessive lipid peroxidation

Box 1 Despite the limited value of measuring blood cytokine levels in understanding pathophysiology and neuroinflammation, blood cytokine levels are used as a dependent variable in many ME/CFS studies, probably due to ease of collection