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132 , e161483 (2022)

An imbalanced gut microbiome can lead to poor absorption of these nutrients, which can directly affect thyroid hormone production and metabolism

[DOI] [PubMed] [Google Scholar] 410.Guen VJ, et al

211,212 For example, age-related upregulation of CXCR4 leads to mislocalization of Tfh cells to the dark zone, along with a significant reduction in the follicular dendritic cell (FDC) network area and a marked decrease in the number of plasma cells