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Verify current regulatory status, as it continues to evolve

( c ) Representative histograms showing CD44 expression on DCs isolated from spleens of chimeric mice by mechanical dissociation

Cytosolic mtDNA then acts as a persistent trigger of innate immune pathways (e.g., cGAS-STING, NLRP3), fueling chronic inflammation that drives accelerated aging and non-AIDS comorbidities despite virological suppression